It is a scary fact that one in two women and one in three men in the United States will develop some form of cancer in their lifetime. One of the hallmarks of many cancers is the occurrence of errors during the cell division process called mitosis. Therefore, critical to enhancing treatments or perhaps even finding a cure for cancer and other diseases, is developing a better understanding of how mitosis works in both healthy and diseased cells.

Rensselaer Polytechnic Institute’s Christopher Cioffi, Ph.D., Thomas and Constance D’Ambra Professor in Organic Chemistry, has received a $2.5 million grant from the National Institutes of Health, along with Konstantin Petrukhin of Columbia University and Gennadiy Moiseyev of Wake Forest University. The grant will enable the team to design a drug to treat Stargardt disease, a rare retinal disorder.

Chunyu Wang, Ph.D., professor of biological sciences at Rensselaer Polytechnic Institute, has added to his body of research on Alzheimer’s disease with significant findings in Angewandte Chemie.

Researchers from Rensselaer Polytechnic Institute (RPI) and Albany Medical College were awarded a $3.3 million grant over five years by the National Cancer Institute to use artificial intelligence (AI) to improve targeted drug therapy in HER2-positive breast cancer treatment. HER2-positive breast cancer tends to grow and spread quickly, but targeted treatments improve outcomes.

Steven Cramer, the William Weightman Walker Professor of Polymer Engineering and a professor in the Isermann Department of Chemical and Biological Engineering at Rensselaer Polytechnic Institute (RPI), has been elected to the National Academy of Engineering for “scientific and technological advances leading to new chromatographic materials, processes, and predictive tools for the purification of biopharmaceuticals.”

In an article published in the Journal of Bone and Mineral Research, researchers at Rensselaer Polytechnic Institute (RPI) Dr. Deepak Vashishth and Joan Llabre, a Ph.D. student in the Department of Biomedical Engineering, presented evidence of a link between Alzheimer’s, osteoporosis, and diabetes. While recent evidence showed loss of bone mineral density with Alzheimer’s disease, this is the first study to demonstrate the effects of the Alzheimer’s disease phenotype on bone quality and link changes in bone and amyloid formation in the brain.

Researchers at Rensselaer Polytechnic Institute (RPI) have been awarded one of 12 grants for space biology research that will advance NASA’s understanding of how organisms respond, acclimate, and adapt in space. These projects will all support NASA’s human space exploration project. 

Propofol is the most commonly used drug to induce general anesthesia. Despite its frequent clinical application, it is poorly understood how propofol causes anesthesia.

Rensselaer Polytechnic Institute Professor Catherine Royer will be honored as a 2023 Society Fellow of the Biophysical Society.

The brain’s ability to clear a protein closely linked to Alzheimer’s disease is tied to our circadian cycle, according to research published today in PLOS Genetics.