Biotechnology and Life Sciences

Study finds link between Alzheimer’s and circadian clock

People who develop Alzheimer’s disease can experience sleep disturbances years before the condition takes hold, but whether one causes the other, or something more complex is afoot, has always proved hard for scientists to determine.

Now, researchers in the US have shed light on the mystery, in work that raises hopes for new therapies, and how “good sleep hygiene” could help to tackle the disease and its symptoms.

Guarding against adversarial machine learning

Pingkun Yan, like many in biomedical research, is a firm believer in the power of artificial intelligence (AI) to improve and potentially revolutionize healthcare technology. On the other hand, he notes, he’s also a realist: For all the hype to become a reality, challenges must be overcome first.

“A lot of people think AI is so capable and that it can solve all of our problems,” says Yan, an assistant professor of biomedical engineering at Rensselaer Polytechnic Institute in Troy, New York. “That may be true in a couple of decades, but right now, it still has weaknesses—we’re really not there yet.”



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Founded in 1824, Rensselaer Polytechnic Institute is America’s first technological research university. Rensselaer encompasses five schools, over 30 research centers, more than 140 academic programs including 25 new programs, and a dynamic community made up of over 6,800 students and 104,000 living alumni. Rensselaer faculty and alumni include upwards of 155 National Academy members, six members of the National Inventors Hall of Fame, six National Medal of Technology winners, five National Medal of Science winners, and a Nobel Prize winner in Physics. With nearly 200 years of experience advancing scientific and technological knowledge, Rensselaer remains focused on addressing global challenges with a spirit of ingenuity and collaboration. To learn more, please visit