The U.S. Food and Drug Administration has approved a new drug for treating schizophrenia and bipolar I disorder that includes samidorphan, a new chemical entity discovered at Rensselaer Polytechnic Institute.
Biotechnology and Life Sciences
Oxygen levels in the world’s temperate freshwater lakes are declining rapidly — faster than in the oceans — a trend driven largely by climate change that threatens freshwater biodiversity and drinking water quality.
As more dissolved organic matter enters lakes across the northeast United States, darkening the lakes in a phenomena called “browning,” new research shows that these waters may be growing less productive and able to sustain less life.
When combined with drugs currently used to treat hepatitis C, the antiviral remdesivir is 10 times more effective in treating cells infected with SARS-CoV-2, the virus that causes COVID-19.
With a prestigious National Science Foundation Faculty Early Career Development (CAREER) grant, researcher Kevin Rose will examine large-scale patterns in concentrations of carbon dioxide (CO2) and dissolved oxygen .
Using a nanopore, researchers have demonstrated the potential to reduce the time required for sequencing a glycosaminoglycan — a class of long chain-linked sugar molecules as important to our biology as DNA — from years to minutes.
Envisioning an animal-free drug supply, scientists have — for the first time — reprogrammed a common bacterium to make a designer polysaccharide molecule used in pharmaceuticals and nutraceuticals.
An antioxidant found in green tea may increase levels of p53, a natural anti-cancer protein, known as the “guardian of the genome” for its ability to repair DNA damage or destroy cancerous cells.
A new grant from the National Institute On Aging at the National Institutes of Health will support ongoing research at Rensselaer Polytechnic Institute to address Alzheimer’s disease caused by gene mutations. According to Chunyu Wang, the principal investigator and an assistant professor of biological sciences at Rensselaer, the project seeks to understand and counter the mechanism that produces Amyloid-Beta 42 peptide in brain cells.
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About Rensselaer Polytechnic Institute
Founded in 1824, Rensselaer Polytechnic Institute is America’s first technological research university. Rensselaer encompasses five schools, over 30 research centers, more than 140 academic programs including 25 new programs, and a dynamic community made up of over 6,800 students and 104,000 living alumni. Rensselaer faculty and alumni include upwards of 155 National Academy members, six members of the National Inventors Hall of Fame, six National Medal of Technology winners, five National Medal of Science winners, and a Nobel Prize winner in Physics. With nearly 200 years of experience advancing scientific and technological knowledge, Rensselaer remains focused on addressing global challenges with a spirit of ingenuity and collaboration. To learn more, please visit www.rpi.edu.