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National Institutes of Health Awards Grant for Enhanced NMR Instrumentation

National Institutes of Health Awards Grant for Enhanced NMR Instrumentation



By Mary L. Martialay

January 7, 2022

The National Institutes of Health High End Instrumentation Grant Program has awarded an equipment grant of $1,315,168 to Rensselaer Polytechnic Institute to upgrade high field 800 MHz Nuclear Magnetic Resonance (NMR) core instrumentation in the Center for Biotechnology and Interdisciplinary Studies (CBIS). The extensive upgrades include new radiofrequency electronics, cryogenic probe and cooling units, temperature-controlled automatic sample changer, and support systems for the 18.8 Tesla superconducting magnet. The upgrade allows Rensselaer to continue to offer state-of-the-art NMR spectroscopy capabilities for chemistry, biochemistry, molecular biology, and material sciences.


The grant was led by Biocomputation and Bioinformatics Constellation Chair Gaetano Montelione, CBIS NMR Core Facility Director Scott McCallum,  Director of CBIS Research Cores Marimar Lopez, and Professor of Biological Sciences Chunyu Wang.


"These new acquisitions and upgrades to Rensselaer CBIS core facilities made over the last year ensure that our faculty and students have access to cutting-end instrumentation, and that we continue to function as a regional resource for science and engineering research," said Dr. Montelione.


This facility will support a consortium of users at Rensselaer, as well as external user groups, including faculty of the State University of New York at Albany, the State University of New York at Buffalo, Albany College of Pharmacy and Health Sciences, Siena College, and Rutgers – The State University of New Jersey.


This NMR upgrade is a part of the larger effort in CBIS to update and equip its research cores with new state-of-the-art technologies. Other additions include a new genomics core facility, a super resolution microscope (STED), a Spectral Computed Tomography (CT) system, and a helium recycling system that supports the supply of the nonrenewable resource critical for the operations of the cryogenically cooled superconducting magnets of the NMR systems.


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Founded in 1824, Rensselaer Polytechnic Institute is America’s first technological research university. Rensselaer encompasses five schools, over 30 research centers, more than 140 academic programs including 25 new programs, and a dynamic community made up of over 6,800 students and 104,000 living alumni. Rensselaer faculty and alumni include upwards of 155 National Academy members, six members of the National Inventors Hall of Fame, six National Medal of Technology winners, five National Medal of Science winners, and a Nobel Prize winner in Physics. With nearly 200 years of experience advancing scientific and technological knowledge, Rensselaer remains focused on addressing global challenges with a spirit of ingenuity and collaboration. To learn more, please visit www.rpi.edu.