Rensselaer Polytechnic Institute Researcher and Nobel Prize-Winning Chemist Pave the Way for Polymer Design
A research study led jointly by Rensselaer Polytechnic Institute’s (RPI) Gaetano Montelione, Ph.D., Professor and Constellation Endowed Chair of Chemistry and Chemical Biology; and David Baker, Ph.D., professor of biochemistry, HHMI investigator, and the director of the Institute for Protein Design (IPD) at the University of Washington School of Medicine; describes a systematic high-throughput design approach for virtual screening and creation of novel polypeptide-based molecules that form regular secondary structures that can be used in biology or materials science research. Baker was recently named a co-recipient of the 2024 Nobel Prize in Chemistry for developing the emerging field of de novo protein design.