ChatGPT has fascinated the public as we begin to explore how generative artificial intelligence (AI) can be useful in our everyday lives. On the back end, scientists are continually advancing AI for potential applications so vast that it may change life as we know it by accelerating scientific and technological developments.

With daylight savings time ending soon, we anticipate a change in the timing of daylight hours with the sunrise occurring earlier in the morning. Already, too many of us get far too little sleep, and disruptions to our circadian cycles like those caused by daylight savings time transitions may make us feel more than tired and out of whack. In the end, there is significant medical data that shows that sudden day/night-time changes may even make us sick.

Rensselaer Polytechnic Institute has established the Office of Strategic Alliances and Translation, a new area within the university that incorporates a number of key translational activities at RPI, including intellectual property and technology licensing, large-scale corporate partnerships, initiation and growth of start-up ventures, and translational campuses, including the Rensselaer Technology Park, as well as translational activities in New York City.

Rensselaer Polytechnic Institute’s Steven Cramer, William Weightman Walker Professor of Polymer Engineering, and Todd Przybycien, professor of chemical and biological engineering, will contribute to a three-year research program led by faculty at Massachusetts Institute of Technology (MIT) that aims to design the world’s first fully integrated, continuous mRNA manufacturing platform. Both Cramer and Przybycien are members of Rensselaer’s Shirley Ann Jackson, Ph.D. Center for Biotechnology and Interdisciplinary Studies. The platform is part of an $82 million effort funded by the U.S. Food and Drug Administration (FDA) Center for Biologics Evaluation and Research.

A team of researchers led by Rensselaer Polytechnic Institute’s Jonathan S. Dordick, Ph.D., Institute Professor of Chemical and Biological Engineering, has illuminated a new possibility for the treatment and prevention of COVID-19 in research published in Communications Biology.

Rensselaer Polytechnic Institute’s Catherine Royer, Constellation Chair Professor of Bioinformatics and Biocomputation at the Shirley Ann Jackson, Ph.D. Center for Biotechnology and Interdisciplinary Studies (CBIS) and professor of biological sciences, has received a grant of over $400,000 from the National Science Foundation to investigate enzymes from organisms living in deep sea environments.

Just as space holds infinite mysteries, when we zoom in at the level of biomolecules (one trillion times smaller than a meter), there is still so much to learn. Rensselaer Polytechnic Institute’s Catherine Royer, Constellation Chair Professor of Bioinformatics and Biocomputation at the Shirley Ann Jackson, Ph.D. Center for Biotechnology and Interdisciplinary Studies (CBIS) and professor of biological sciences, is dedicated to understanding the conformational landscapes of biomolecules and how they modulate cell function. When biomolecules receive certain inputs, it can cause the atoms to rearrange and the biomolecule to change shape. This change in shape affects their function in cells, so understanding conformational dynamics is critical for drug development.

It is a scary fact that one in two women and one in three men in the United States will develop some form of cancer in their lifetime. One of the hallmarks of many cancers is the occurrence of errors during the cell division process called mitosis. Therefore, critical to enhancing treatments or perhaps even finding a cure for cancer and other diseases, is developing a better understanding of how mitosis works in both healthy and diseased cells.

Rensselaer Polytechnic Institute’s Ge Wang, Ph.D. — Clark & Crossan Endowed Chair Professor, director of the Biomedical Imaging Center within the Shirley Ann Jackson, Ph.D. Center for Biotechnology and Interdisciplinary Studies, and this year’s winner of the Wiley Distinguished Faculty Award — and Albany Medical College’s Joshua Goldwag ’20, a medical student and previously Ge Wang’s research student at Rensselaer, have jointly published an article in Nature Machine Intelligence on the DishBrain experiment and its applications. Last October, Cortical Labs revealed that they “taught” human and mouse cells in a dish to work together to play the Pong game by providing feedback to the cells. They called it DishBrain. It was the first time that scientists stimulated biological cells in a structured/feedback-driven way.

Chunyu Wang, Ph.D., professor of biological sciences at Rensselaer Polytechnic Institute, has added to his body of research on Alzheimer’s disease with significant findings in Angewandte Chemie.